To the best of our knowledge there is no evidence available to support or contradict the routine of offering a second renal allograft to elderly patients with graft-failure. We believe it is important to explore this issue both for clinical and policy reasons and consequently we designed this study to evaluate the survival outcomes of kidney re-transplantation in patients older than 65 years and compare them with age- and time-matched first kidney transplant recipients.
During follow-up there were 20 (43%) graft losses in TX2 and 327 (48%) in TX1. Death with functioning graft was the predominant cause of graft loss in both groups being responsible for 14 (70%) graft losses in TX2 and 257 (79%) in TX1. Rejection was the cause of graft loss in two patients (10%) in TX2 and 31 patients (9.5%) in TX 1. All other causes were accounted for and because of low numbers comparisons between groups are of limited value and were not performed.
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